Article
Analysis of microbiome in gastrointestinal stromal tumors: Looking for different players in tumorigenesis and novel therapeutic options.
Cancer science - 1 Aug 2022
Ravegnini Gloria, Fosso Bruno, Ricci Riccardo, Gorini Francesca, Turroni Silvia, Serrano Cesar, Pilco-Janeta Daniel F, Zhang Qianqian, Zanotti Federica, De Robertis Mariangela, Nannini Margherita, Pantaleo Maria Abbondanza, Hrelia Patrizia, Angelini Sabrina
Abstract excerpt
Preclinical forms of gastrointestinal stromal tumor (GIST), small asymptomatic lesions, called microGIST, are detected in approximately 30% of the general population. Gastrointestinal stromal tumor driver mutation can be already detected in microGISTs, even if they do not progress into malignant cancer; these mutations are necessary, but insufficient events to foster tumor progression. Here we profiled the tissue...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.