Whole-genome sequencing of SARS-CoV-2 reveals diverse mutations in circulating Alpha and Delta variants during the first, second, and third waves of COVID-19 in South Kivu, east of the Democratic Republic of the Congo.

doi:10.1016/j.ijid.2022.05.041

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Whole-genome sequencing of SARS-CoV-2 reveals diverse mutations in circulating Alpha and Delta variants during the first, second, and third waves of COVID-19 in South Kivu, east of the Democratic Republic of the Congo.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Sept 2022

Ntagereka Patrick Bisimwa, Oyola Samuel O, Baenyi Simon Patrick, Rono Gilbert Kibet, Birindwa Ahadi Bwihangane, Shukuru Dieudonné Wasso, Baharanyi Tshass Chasinga, Kashosi Théophile Mitima, Buhendwa Jean-Paul Cikwanine, Bisimwa Parvine Basimane, Kusinza Aline Byabene, Basengere Rodrigue Ayagirwe, Mukwege Denis

Abstract excerpt

OBJECTIVES: We used whole-genome sequencing of SARS-CoV-2 to identify variants circulating in the Democratic Republic of the Congo and obtain molecular information useful for diagnosis, improving treatment, and general pandemic control strategies. METHODS: A total of 74 SARS-CoV-2 isolates were sequenced using Oxford Nanopore platforms. Generated reads were processed to obtain consensus genome sequences....

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PMID: 35598737
DOI: 10.1016/j.ijid.2022.05.041
PMCID: PMC9119719

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