Article
Whole genome sequencing of clinical specimens reveals the genomic diversity of porcine reproductive and respiratory syndrome viruses emerging in China.
Transboundary and emerging diseases - 1 Sept 2022
Xing Jiabao, Zheng Zezhong, Cao Xinyu, Wang Zhiyuan, Xu Zhiying, Gao Han, Liu Jing, Xu Sijia, Lin Jinsen, Chen Shengnan, Wang Heng, Zhang Guihong, Sun Yankuo
Abstract excerpt
The Porcine reproductive and respiratory syndrome virus (PRRSV), a single (+) RNA virus, is characterized by high genome variability and constant evolution. Owing to increasingly complex mutations, there is a growing difficulty in accessing the whole genome. Additionally, there is limited knowledge on PRRSV intra-host nucleotide variants, which may reflect the complex viral-host dynamics. Here, we performed...
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