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CancerVar: An artificial intelligence-empowered platform for clinical interpretation of somatic mutations in cancer.

Science advances - 6 May 2022

Li Quan, Ren Zilin, Cao Kajia, Li Marilyn M, Wang Kai, Zhou Yunyun

Abstract excerpt

Several knowledgebases are manually curated to support clinical interpretations of thousands of hotspot somatic mutations in cancer. However, discrepancies or even conflicting interpretations are observed among these databases. Furthermore, many previously undocumented mutations may have clinical or functional impacts on cancer but are not systematically interpreted by existing knowledgebases. To address these...

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Artificial Intelligence
Mutation
Neoplasms

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35544644
DOI: 10.1126/sciadv.abj1624
PMCID: PMC9075800

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