Article
ABO genotype alters the gut microbiota by regulating GalNAc levels in pigs.
Nature - 1 Jun 2022
Yang Hui, Wu Jinyuan, Huang Xiaochang, Zhou Yunyan, Zhang Yifeng, Liu Min, Liu Qin, Ke Shanlin, He Maozhang, Fu Hao, Fang Shaoming, Xiong Xinwei, Jiang Hui, Chen Zhe, Wu Zhongzi, Gong Huanfa, Tong Xinkai, Huang Yizhong, Ma Junwu, Gao Jun, Charlier Carole, Coppieters Wouter, Shagam Lev, Zhang Zhiyan, Ai Huashui, Yang Bin, Georges Michel, Chen Congying, Huang Lusheng
Abstract excerpt
The composition of the intestinal microbiome varies considerably between individuals and is correlated with health1. Understanding the extent to which, and how, host genetics contributes to this variation is essential yet has proved to be difficult, as few associations have been replicated, particularly in humans2. Here we study the effect of host genotype on the composition of the intestinal microbiota in a...
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