Article
Safety of Tepotinib in Patients With MET Exon 14 Skipping NSCLC and Recommendations for Management.
Clinical lung cancer - 1 Jun 2022
Veillon Remi, Sakai Hiroshi, Le Xiuning, Felip Enriqueta, Cortot Alexis B, Smit Egbert F, Park Keunchil, Griesinger Frank, Britschgi Christian, Wu Yi-Long, Melosky Barbara, Baijal Shobhit, Jr Gilberto de Castro, Sedova Michaela, Berghoff Karin, Otto Gordon, Paik Paul K
Abstract excerpt
INTRODUCTION: The MET inhibitor tepotinib demonstrated durable clinical activity in patients with advanced MET exon 14 (METex14) skipping NSCLC. We report detailed analyses of adverse events of clinical interest (AECIs) in VISION, including edema, a class effect of MET inhibitors. PATIENTS AND METHODS: Incidence, management, and time to first onset/resolution were analyzed for all-cause AECIs, according to...
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