Article
IDH1 inhibitor-induced neutrophilic dermatosis in a patient with acute myeloid leukemia.
Cancer treatment and research communications - 1 Jan 2022
Dunn-Valadez Sydney, Bathini Srilakshmi, Elston Carly, Rangaraju Sravanti, Stasi Antonio Di, Worth Sarah, Morlote Diana, Harada Shuko, Vachhani Pankit
Abstract excerpt
Ivosidenib is an oral inhibitor of mutant Isocitrate dehydrogenase 1 (IDH1). It is approved for treatment of patients with relapsed or refractory IDH1-mutated acute myeloid leukemia (AML) and patients with newly diagnosed IDH1-mutated AML who are 75 years or older or those who are ineligible to receive intensive chemotherapy. While generally well tolerated, differentiation syndrome has been reported in 15-20% of...
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