Metagenomic sequencing reveals time, host, and body compartment-specific viral dynamics after lung transplantation

Abstract excerpt

BACKGROUND: The virome of lung transplant recipients (LTRs) under immunosuppressive therapy is dominated by non-pathogenic Anelloviridae and further includes several pathogenic viruses such as Herpesviruses or respiratory viruses. It is unclear whether the donor-derived virome in the transplanted lung influences recipient virome dynamics in other body compartments and if so, to which degree. Likewise, it is...

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