Article
Genetic Testing for All: Overcoming Disparities in Ovarian Cancer Genetic Testing.
American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting - 1 Apr 2022
Frey Melissa K, Finch Amy, Kulkarni Amita, Akbari Mohammad R, Chapman-Davis Eloise
Abstract excerpt
Nearly 3% of the population carries genetic variants that lead to conditions that include hereditary breast and ovarian cancer and Lynch syndrome. These pathogenic variants account for approximately 20% of ovarian cancer cases, and those with germline pathogenic variants have an odds ratio between 4 and 40 for developing ovarian cancer compared with noncarriers. Given the high prevalence of genetic variants,...
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