Article
Three Third-Generation Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer: Similarities and Differences.
Cancer investigation - 1 Aug 2022
Chen Ling, Zhou Yangqingqing, Gan Chaosheng, Wang XiaoLi, Liu Yihui, Dong Chunhui, He Ruiyuan, Yang Jin
Abstract excerpt
Osimertinib, almonertinib and furmonertinib are third-generation epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) approved for non-small cell lung cancer (NSCLC) patients with EGFR T790M mutation. This article reviews research advances in pharmacokinetics, pharmacodynamics, treatment-related adverse events, and other aspects related to the three EGFR-TKIs were systematically reviewed in...
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