Article
The genomic landscape of blood groups in Indigenous Australians in remote communities.
Transfusion - 1 May 2022
Jadhao Sudhir, Hoy Wendy, Lee Simon, Patel Hardip R, McMorran Brendan J, Flower Robert L, Nagaraj Shivashankar H
Abstract excerpt
BACKGROUND: Red blood cell (RBC) membrane-associated blood group systems are clinically significant. Alloimmunisation is a persistent risk associated with blood transfusion owing to the antigen polymorphisms among these RBC-associated blood groups. Next-generation sequencing (NGS) offers an opportunity to characterize the blood group variant profile of a given individual. Australia comprises a large multiethnic...
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