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The cell‐free DNA virome of 108,349 Dutch pregnant women

11 Apr 2022

Abstract excerpt

OBJECTIVE: Viral infections during pregnancy are a major health concern to mother and fetus. By repurposing cell-free Non Invasive Prenatal Testing (NIPT) sequencing data, we investigated prevalence and abundance of viral DNA in a cohort of 108,349 pregnant women. METHOD: Cell-free DNA (cfDNA) sequencing reads that did not map to any of the human chromosomes or mitochondrial DNA of the human reference genome...

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PMID: 35403226
DOI: 10.1002/pd.6143

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