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Article

Real-world Afatinib Outcomes in Advanced Non-small Cell Lung Cancer Harboring EGFR Mutations.

Anticancer research - 1 Apr 2022

Chen Chi-Han, Chang John Wen-Cheng, Chang Ching-Fu, Huang Chen-Yang, Yang Cheng-Ta, Kuo Chih-Hsi Scott, Fang Yueh-Fu, Hsu Ping-Chih, Wu Chiao-En

Abstract excerpt

BACKGROUND/AIM: Afatinib is a standard treatment for patients with advanced non-small cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR) mutations. Osimertinib can overcome the treatment resistance-associated EGFR T790M mutation, and the sequence of afatinib followed by osimertinib is an effective therapeutic strategy for NSCLC patients. This study comprehensively evaluated the outcomes of...

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PMID: 35347039
DOI: 10.21873/anticanres.15697

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