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Cervicovaginal DNA Virome Alterations Are Associated with Genital Inflammation and Microbiota Composition

28 Mar 2022

Abstract excerpt

HPV infection is an established risk factor for cervical cancer. However, more broadly, the role of the cervicovaginal virome in cervical cancer progression is not well understood. Here, we identified cervicovaginal DNA virome alterations associated with local microenvironment factors (vaginal microbiota and genital inflammation) that influence HPV persistence and progression to cervical cancer. These findings...

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PMID: 35343798
DOI: 10.1128/msystems.00064-22

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