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PPRV-Induced Autophagy Facilitates Infectious Virus Transmission by the Exosomal Pathway

23 Mar 2022

Abstract excerpt

Autophagy plays an important role in PPRV pathogenesis. The role of exosomes in viral infections is beginning to be appreciated. The present study examined the role of autophagy in secretion of infectious PPRV from Vero cells. Our data provided the first direct evidence that ATG7-mediated autophagy enhances exosome secretion and exosome-mediated PPRV transmission. TSG101 may be involved in the sorting of the...

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PMID: 35319226
DOI: 10.1128/jvi.00244-22

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