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Article

Mutation of NtNRAMP3 improves cadmium tolerance and its accumulation in tobacco leaves by regulating the subcellular distribution of cadmium.

Journal of hazardous materials - 15 Jun 2022

Jia Hongfang, Yin Zhuoran, Xuan Dongdong, Lian Wenli, Han Dan, Zhu Zitong, Li Chenyi, Li Chang, Song Zhaopeng

Abstract excerpt

Cadmium (Cd) is a harmful element that affects plant growth and development. Genetic improvements could be applied for enhancing Cd tolerance and accumulation in plants. Here, a novel Cd stress-induced gene, NtNRAMP3, was identified in tobacco. We constructed two NtNRAMP3-knockout (KO) tobacco lines using the CRISPR/Cas9 system, which enhanced Cd tolerance and Cd accumulation in tobacco leaves compared with those...

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PMID: 35313160
DOI: 10.1016/j.jhazmat.2022.128701

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