Article
Elexacaftor/Tezacaftor/Ivacaftor as a Bridge to Lung Retransplant in a Recipient With Cystic Fibrosis.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation - 1 Apr 2022
FitzMaurice Thomas Simon, Nazareth Dilip, Iyer Kapil, Walshaw Martin, Al-Aloul Mohamed
Abstract excerpt
The triple-combination cystic fibrosis transmembrane conductance regulator modulator elexacaftor/- tezacaftor/ivacaftor is known to improve lung function and have extrapulmonary benefits in people with cystic fibrosis. However, there is limited evidence for its use in patients with cystic fibrosis after lung transplant, where the donor lung expresses normal levels of the cystic fibrosis transmembrane conductance...
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