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Article

Identification and Validation of Immune Infiltration Phenotypes in Laryngeal Squamous Cell Carcinoma by Integrative Multi-Omics Analysis.

Frontiers in immunology - 1 Jan 2022

Yan Li, Song Xiaole, Yang Gang, Zou Lifen, Zhu Yi, Wang Xiaoshen

Abstract excerpt

Background: Laryngeal squamous cell carcinoma (LSCC) is one of the world's most common head and neck cancer. However, the immune infiltration phenotypes of LSCC have not been well investigated. Methods: The multi-omics data of LSCC were obtained from the TCGA (n=111) and GEO (n=57) datasets. The infiltrations of the 24 immune cell populations were calculated using the GSVA method. Then LSCC samples with different...

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Identifiers

PMID: 35281069
DOI: 10.3389/fimmu.2022.843467
PMCID: PMC8907422

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