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Genetic characterization and pathogenicity of a novel recombinant PRRSV from lineage 1, 8 and 3 in China failed to infect MARC-145 cells.

Microbial pathogenesis - 1 Apr 2022

Li Yang, Jiao Dian, Jing Yang, He Yuan, Han Weiguo, Li Zhiwei, Ma Zhiqian, Feng Yingtong, Xiao Shuqi

Abstract excerpt

The diversity of porcine reproductive and respiratory syndrome virus (PRRSV) in China is increasing rapidly along with mutation and recombination. Recombination could occur between inter- and intra-lineage of PRRSV, which accelerated the complexity of pathogenicity and cell tropism of the recombinant strain. In the present study, a novel PRRSV strain named HN-YL1711 was isolated from a pig farm suffering from...

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PMID: 35271985
DOI: 10.1016/j.micpath.2022.105469

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