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Article

MicroRNAs as the critical regulators of tyrosine kinase inhibitors resistance in lung tumor cells.

Cell communication and signaling : CCS - 9 Mar 2022

Maharati Amirhosein, Zanguei Amir Sadra, Khalili-Tanha Ghazaleh, Moghbeli Meysam

Abstract excerpt

Lung cancer is the second most common and the leading cause of cancer related deaths globally. Tyrosine Kinase Inhibitors (TKIs) are among the common therapeutic strategies in lung cancer patients, however the treatment process fails in a wide range of patients due to TKIs resistance. Given that the use of anti-cancer drugs can always have side effects on normal tissues, predicting the TKI responses can provide...

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Share to Carcinoma, Non-Small-Cell Lung
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35264191
DOI: 10.1186/s12964-022-00840-4
PMCID: PMC8905758

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