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Article

FKRP directed fibronectin glycosylation: A novel mechanism giving insights into muscular dystrophies?

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 May 2022

Boyd Andrew, Montandon Margo, Wood Alasdair J, Currie Peter D

Abstract excerpt

The recently uncovered role of Fukutin-related protein (FKRP) in fibronectin glycosylation has challenged our understanding of the basis of disease pathogenesis in the muscular dystrophies. FKRP is a Golgi-resident glycosyltransferase implicated in a broad spectrum of muscular dystrophy (MD) pathologies that are not fully attributable to the well-described α-Dystroglycan hypoglycosylation. By revealing a new role...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 35229908
DOI: 10.1002/bies.202100270

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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