Article
Spread of Gamma (P.1) Sub-Lineages Carrying Spike Mutations Close to the Furin Cleavage Site and Deletions in the N-Terminal Domain Drives Ongoing Transmission of SARS-CoV-2 in Amazonas, Brazil.
Microbiology spectrum - 23 Feb 2022
Naveca Felipe Gomes, Nascimento Valdinete, Souza Victor, Corado André de Lima, Nascimento Fernanda, Silva George, Mejía Matilde Contreras, Brandão Maria Júlia, Costa Ágatha, Duarte Débora, Pessoa Karina, Jesus Michele, Gonçalves Luciana, Fernandes Cristiano, Mattos Tirza, Abdalla Ligia, Santos João Hugo, Martins Alex, Chui Fabiola Mendonça, Val Fernando Fonseca, de Melo Gisely Cardoso, Xavier Mariana Simão, Sampaio Vanderson de Souza, Mourão Maria Paula, Lacerda Marcus Vinícius, Batista Érika Lopes Rocha, Magalhães Alessandro Leonardo Álvares, Dábilla Nathânia, Pereira Lucas Carlos Gomes, Vinhal Fernando, Miyajima Fabio, Dias Fernando Braga Stehling, Dos Santos Eduardo Ruback, Coêlho Danilo, Ferraz Matheus, Lins Roberto, Wallau Gabriel Luz, Delatorre Edson, Gräf Tiago, Siqueira Marilda Mendonça, Resende Paola Cristina, Bello Gonzalo
Abstract excerpt
The Amazonas was one of the most heavily affected Brazilian states by the COVID-19 epidemic. Despite a large number of infected people, particularly during the second wave associated with the spread of the Variant of Concern (VOC) Gamma (lineage P.1), SARS-CoV-2 continues to circulate in the Amazonas. To understand how SARS-CoV-2 persisted in a human population with a high immunity barrier, we generated 1,188...
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