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Article

Genetic polymorphisms in CYP19A1 and ESR1 are associated with serum CK activity after prolonged running in men.

Journal of applied physiology (Bethesda, Md. : 1985) - 1 Apr 2022

Kumagai Hiroshi, Miyamoto-Mikami Eri, Takaragawa Mizuki, Kuriki Kiyonori, Goto Chiho, Shibata Kiyoshi, Yamada Norihiro, Hosono Akihiro, Fuku Mizuho, Suzuki Sadao, Fuku Noriyuki

Abstract excerpt

This study aimed to clarify 1) the influence of genetic polymorphisms in the cytochrome P450 aromatase gene (CYP19A1) on circulating estradiol levels in men and 2) whether estrogen-related genetic polymorphisms, such as the CYP19A1 rs936306 and estrogen receptor-α (ESR1) rs2234693 polymorphisms, predict exercise-induced serum creatine kinase (CK) activity, which is an index of skeletal muscle membrane disruption....

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Identifiers

PMID: 35175101
DOI: 10.1152/japplphysiol.00374.2021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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