Article
Contributions of epigenetic inheritance to the predisposition of major psychiatric disorders: Theoretical framework, evidence, and implications.
Neuroscience and biobehavioral reviews - 1 Apr 2022
Varela Roger B, Cararo José Henrique, Tye Susannah J, Carvalho Andre F, Valvassori Samira S, Fries Gabriel R, Quevedo João
Abstract excerpt
Susceptibility to psychiatric disorders seems to be influenced by environmental disturbances throughout all stages of life. Epigenetics is described as a key "bridge" between gene and environment, shaping gene expression and phenotype in response to environmental influences. For a long time, it was believed the epigenetic information could not be transmitted from one generation to the next, however, recent...
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