Article
Characterization and functional analysis of the adipose tissue-derived stromal vascular fraction of pediatric patients with osteogenesis imperfecta.
Scientific reports - 14 Feb 2022
Tauer Josephine T, Al-Jallad Hadil, Umebayashi Mayumi, Bakhsh Dena, Rauch Damian, Tran Simon D, Rauch Frank, Hamdy Reggie
Abstract excerpt
Pediatric patients with Osteogenesis Imperfecta (OI), a heritable connective tissue disorder, frequently suffer from long bone deformations. Surgical correction often results in bone non-unions, necessitating revision surgery with autogenous bone grafting using bone-marrow-derived stem cells (BM-SC) to regenerate bone. BM-SC harvest is generally invasive and limited in supply; thus, adipose tissue's stromal...
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