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Establishment of iPS cell line (KLRMMEi002-A) by reprogramming peripheral blood mononuclear cells from a patient with USH2A-associated Usher syndrome.

Stem cell research - 1 Apr 2022

Liang Liying, Xue Yunxia, Su Caiying, Wang Jianing, Chen Luyin, Su Ting, Ke Jianyu, Xie Linyao, Cui Zekai, Yu Quan, Chan Hon Fai, Zhong Jingxiang, Guo Yonglong, Chen Jiansu

Abstract excerpt

USH type 2 (USH2) is an autosomal recessive disorder that is characterized by inherited retinopathies and sensorineural hearing loss. USH type 2 (USH2) is frequently caused by USH2A mutations, which account for 74-90% of USH2 cases. We used peripheral blood mononuclear cells (PBMCs) from a USH2 patient with a USH2A gene mutation (c.8559-2A > G) to create an induced pluripotent stem (iPS) cell line. The...

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Identifiers

PMID: 35152177
DOI: 10.1016/j.scr.2022.102699

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Establishment of iPS cell line (KLRMMEi002-A) by reprogramming peripheral blood mononuclear cells from a patient with USH2A-associated Usher syndrome.PMID 35152177Read ↗

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