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Article

Constant light exposure alters gut microbiota and short-/medium-chain fatty acids and aggravates PCOS-like traits in HFD-fed rats.

Obesity (Silver Spring, Md.) - 1 Mar 2022

Yue Fangzhi, Xing Lin, Wu Shanyu, Wei Lin, Zhou Zhijun, Shi Ying, Lam Sin Man, Shui Guanghou, Xiang Xingwei, Russell Ryan, Zhang Dongmei

Abstract excerpt

OBJECTIVE: This study investigated the effects of constant light exposure on polycystic ovary syndrome (PCOS)-like endocrine and metabolic changes in high-fat diet (HFD)-fed rats and to elucidate the related microbiotic mechanisms. METHODS: A total of 32 female Sprague-Dawley rats were divided into four groups (n = 8 each): rats on a normal chow diet with standard light-dark cycle, rats on a normal chow diet with...

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Identifiers

PMID: 35128797
DOI: 10.1002/oby.23380

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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