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Article

Liver-specific LINC01146, a promising prognostic indicator, inhibits the malignant phenotype of hepatocellular carcinoma cells both in vitro and in vivo.

Journal of translational medicine - 31 Jan 2022

Ma Xiaoyun, Mo Meile, Tan Chao, Tan Jennifer Hui Juan, Huang Huishen, Liu Bihu, Huang Dongping, Liu Shun, Zeng Xiaoyun, Qiu Xiaoqiang

Abstract excerpt

BACKGROUND: Long non-coding RNAs (lncRNAs) are involved in the development of hepatocellular carcinoma (HCC). We aimed to investigate the function of LINC01146 in HCC. METHODS: The expression of LINC01146 in HCC tissues was explored via The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases and was verified using quantitative real-time polymerase chain reaction (qRT-PCR) in our HCC cohort....

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Share to Carcinoma, Hepatocellular
Share to Cell Line, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Movement

Share to Cell Proliferation

Share to Gene Expression Regulation, Neoplastic

Share to Liver Neoplasms

Share to Mice, Nude

Share to RNA, Long Noncoding

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Identifiers

PMID: 35101062
DOI: 10.1186/s12967-021-03225-2
PMCID: PMC8802422

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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