A capillary electrophoresis-based multiplex PCR assay for expanded carrier screening in the eastern Han Chinese population

Abstract excerpt

Expanded carrier screening, a type of reproductive genetic testing for couples, has gained tremendous popularity for assessing the risk of passing on certain genetic conditions to offspring. Here, a carrier screening assay for 448 pathogenic variants was developed using capillary electrophoresis-based multiplex PCR technology. The capillary electrophoresis-based multiplex PCR assay achieved a sensitivity,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cystic Fibrosis Research Advances
• Share to Folate and B Vitamins Research
• Share to Genomic variations and chromosomal abnormalities