Article
Genetic control of extraglandular aromatase activity in the chicken.
Steroids - 1 Jan 2000
Wilson J D, George F W, Leshin M
Abstract excerpt
Feminization of feathers in the Sebright cock is the result of increase in the activity of skin aromatase. This increased estrogen synthesis is the consequence of an autosomal dominant mutation that causes an increase in the specific androgen-binding cytochrome P450 oxidase involved in the reaction. Since this oxidase appears to be kinetically indistinguishable from the activity in control ovary we believe that...
Topics
- Androgens
- Animals
- Aromatase
- Chickens
- Estrogens
- Feathers
- Gene Expression Regulation
- Male
- Mutation
- Sex Factors
- Skin