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Circular RNA CUL2 regulates the development of colorectal cancer by modulating apoptosis and autophagy via miR-208a-3p/PPP6C

13 Jan 2022

Abstract excerpt

Aim: To explore the function of circular RNA CUL2 (circCUL2) in colorectal cancer progression. Method: RT-PCR was carried out to detect the expression of circCUL2 in colorectal cancer tissues and cell lines. Western blot and immunofluorescence were used to determine the level of autophagy. CCK-8, clone formation assay, and EdU staining were used to assess the proliferation ability. Luciferase assay verified the...

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PMID: 35027503
DOI: 10.18632/aging.203827

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