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The gut microbiota can orchestrate the signaling pathways in colorectal cancer

10 Jan 2022

Abstract excerpt

Current evidence suggests that bacteria contribute to the development of certain cancers, such as colorectal cancer (CRC), partly by stimulating chronic inflammation. However, little is known about the bacterial impact on molecular pathways in CRC. Recent studies have demonstrated how specific bacteria can influence the major CRC-related pathways, i.e., Wnt, PI3K-Akt, MAPK, TGF-β, EGFR, mTOR, and p53. In order to...

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PMID: 35007370
DOI: 10.1111/apm.13206

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