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Comprehensive analysis of a TNF family based-signature in diffuse gliomas with regard to prognosis and immune significance

9 Jan 2022

Abstract excerpt

BACKGROUND: Several studies have shown that members of the tumor necrosis factor (TNF) family play an important role in cancer immunoregulation, and trials targeting these molecules are already underway. Our study aimed to integrate and analyze the expression patterns and clinical significance of TNF family-related genes in gliomas. METHODS: A total of 1749 gliomas from 4 datasets were enrolled in our study,...

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PMID: 35000592
DOI: 10.1186/s12964-021-00814-y

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