Article
[The value of combined detection of HbA2 and HbF for the screening of thalassemia among individuals of childbearing ages].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 10 Jan 2022
Zhuang Qianmei, Wang Geng, Wang Yuanbai, Zhuang Jianlong, Jiang Yuying, Huang Hailong, Xu Liangpu
Abstract excerpt
OBJECTIVE: To assess the application value of combined detection of HbA2 and HbF for the screening of thalassemia among a population of childbearing age in Quanzhou, Fujian, and determine the optimal cut-off values for the region. METHODS: Capillary hemoglobin electrophoresis and genetic testing for α and β globin gene mutations were simultaneously carried out on 11 428 patients with suspected thalassemia....
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