Article
Generation of an induced pluripotent stem cell line (SYSUi005-A) from a patient with hypertrophic cardiomyopathy.
Stem cell research - 1 Jan 2022
Zhang Chi, Shi Jian, Zhang Zhen, Zhao Qianqian, Xie Manting, Chen Ying, Xiang Qiuling
Abstract excerpt
Hypertrophic cardiomyopathy (HCM) is characterized by impaired energy metabolism irrespective of the degree of hypertrophy. Here, we reprogrammed peripheral blood mononuclear cells (PBMCs) isolated from peripheral blood of a patient who suffered from hypertrophic cardiomyopathy, into pluripotent stem cells (iPSC) (SYSUi005-A) using Sendai-virus. The established hiPSC line displayed a normal 46XY karyotype,...
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