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Article

High rate of abnormal findings in Prenatal Exome Trio in low risk pregnancies and apparently normal fetuses

17 Dec 2021

Abstract excerpt

OBJECTIVE: Data on the value of exome sequencing in fetuses with no structural anomalies are limited, especially in the early stages of pregnancy and in low risk pregnancies. We investigated the yield of targeted clinical prenatal trio exome sequencing (pES) in pregnancies with and without fetal structural anomalies. METHODS: We performed pES in 353 pregnancies: Group 1 included 143 pregnancies with high clinical...

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Share to Assisted Reproductive Technology and Twin Pregnancy
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34918830
DOI: 10.1002/pd.6077

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