Article
Deep dissection of the antiviral immune profile of patients with COVID-19.
Communications biology - 16 Dec 2021
Atanackovic Djordje, Avila Stephanie V, Lutfi Forat, de Miguel-Perez Diego, Fan Xiaoxuan, Sanchez-Petitto Gabriela, Vander Mause Erica, Siglin Jonathan, Baddley John, Mannuel Heather D, Alkhaldi Hanan, Hankey Kim G, Lapidus Rena, Kleinberg Michael, Rabin Joseph, Shanholtz Carl, Rolfo Christian, Rapoport Aaron P, Dahiya Saurabh, Luetkens Tim
Abstract excerpt
In light of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) variants potentially undermining humoral immunity, it is important to understand the fine specificity of the antiviral antibodies. We screened 20 COVID-19 patients for antibodies against 9 different SARS-CoV-2 proteins observing responses against the spike (S) proteins, the receptor-binding domain (RBD), and the nucleocapsid (N) protein...
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