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Cumulus Cell DNA Damage as an Index of Human Oocyte Competence

14 Dec 2021

Abstract excerpt

The determination of oocyte quality is crucial for achieving effective syngamy post-sperm injection and embryonic development. Cumulus cells (CCs) have been proposed as biomarkers of oocyte quality because of their close bio-dynamic relationship with the oocyte. To determine the quality of the oocyte, CCs were sampled during oocyte preparation for ICSI to determine a CC DNA fragmentation index (CCDFI) of each...

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PMID: 34907517
DOI: 10.1007/s43032-021-00817-7

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