Article
Novel SNPs and haplotypes identified in the CD4 gene and their influence on deregressed MACE EBV indexes of milk-related traits in Simmental breed.
The Journal of dairy research - 1 Nov 2021
Napolitano Francesco, Grandoni Francesco, De Matteis Giovanna, Degano Lorenzo, Vicario Daniele, Buttazzoni Luca
Abstract excerpt
Cluster of differentiation 4 (CD4) is the accessory protein non-covalently bound to the T cell receptor that recognizes an invariant region of MHC class II on antigen presenting cells. Its cytoplasmic tail, physically associated with a protein tyrosine kinase, is important in the activation of helper/inducer T lymphocytes. In Bos taurus, CD4 gene is located on chromosome 5 from which two isoforms are transcribed,...
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