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Article

Computational analysis of cancer genome sequencing data.

Nature reviews. Genetics - 1 May 2022

Cortés-Ciriano Isidro, Gulhan Doga C, Lee Jake June-Koo, Melloni Giorgio E M, Park Peter J

Abstract excerpt

Distilling biologically meaningful information from cancer genome sequencing data requires comprehensive identification of somatic alterations using rigorous computational methods. As the amount and complexity of sequencing data have increased, so has the number of tools for analysing them. Here, we describe the main steps involved in the bioinformatic analysis of cancer genomes, review key algorithmic...

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PMID: 34880424
DOI: 10.1038/s41576-021-00431-y

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