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Article

SARS-CoV-2 genetic variations associated with COVID-19 pathogenicity.

Microbial genomics - 1 Dec 2021

Aiewsakun Pakorn, Nilplub Patrawee, Wongtrakoongate Patompon, Hongeng Suradej, Thitithanyanont Arunee

Abstract excerpt

In this study, we performed genome-wide association analyses on SARS-CoV-2 genomes to identify genetic mutations associated with pre-symptomatic/asymptomatic COVID-19 cases. Various potential covariates and confounding factors of COVID-19 severity, including patient age, gender and country, as well as virus phylogenetic relatedness were adjusted for. In total, 3021 full-length genomes of SARS-CoV-2 generated from...

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Identifiers

PMID: 34870573
DOI: 10.1099/mgen.0.000734
PMCID: PMC8767342

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