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Pediatric COVID-19 patients in South Brazil show abundant viral mRNA and strong specific anti-viral responses

25 Nov 2021

Abstract excerpt

Abstract COVID-19 manifests as a milder disease in children than adults, but the underlying mechanisms are not fully characterized. Here we assess the difference in cellular or humoral immune responses of pediatric and adult COVID-19 patients to see if these factors contribute to the severity dichotomy. Children’s non-specific immune profile is dominated by naive lymphocytes and HLA-DR high CX3CR1 low dendritic...

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PMID: 34824230
DOI: 10.1038/s41467-021-27120-y

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