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Long noncoding RNA SGO1-AS1 inactivates TGFβ signaling by facilitating TGFB1/2 mRNA decay and inhibits gastric carcinoma metastasis

27 Oct 2021

Abstract excerpt

BACKGROUND: Although thousands of long noncoding RNAs (lncRNAs) have been annotated, only a few lncRNAs have been characterized functionally. In this study, we aimed to identify novel lncRNAs involved in the progression of gastric carcinoma (GC) and explore their regulatory mechanisms and clinical significance in GC. METHODS: A lncRNA expression microarray was used to identify differential lncRNA expression...

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PMID: 34706749
DOI: 10.1186/s13046-021-02140-0

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