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The Microbiome in Autoimmune Liver Diseases: Metagenomic and Metabolomic Changes

8 Oct 2021

Abstract excerpt

Recent studies have identified the critical role of microbiota in the pathophysiology of autoimmune liver diseases (AILDs), including autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), and primary sclerosing cholangitis (PSC). Metagenomic studies reveal significant decrease of gut bacterial diversity in AILDs. Although profiles of metagenomic vary widely, Veillonella is commonly enriched in AIH, PBC,...

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PMID: 34690796
DOI: 10.3389/fphys.2021.715852

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