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Immune and nonimmune mechanisms mediate the mental stress-induced tumor growth in a xenograft model of breast cancer

23 Oct 2021

Abstract excerpt

Excess mental stress may harm health, and even accelerate cancer initiation and progression. One fourth of breast cancer patients suffer mental stress including anxiety, sadness, or depression, which negatively affect prognosis and survival. However, the regulatory mechanism is yet to be determined. Herein, we applied unpredictable stress stimuli to the breast tumor-bearing mice to establish a xenograft model of...

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PMID: 34689156
DOI: 10.1038/s41419-021-04280-9

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