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Article

Viscous Cervical Environment-on-a-Chip for Selecting High-Quality Sperm from Human Semen

10 Oct 2021

Abstract excerpt

When ejaculated sperm travels through the vagina to the uterus, mucus secreted by the cervical canal generally filters out sperm having low motility and poor morphology. To investigate this selection principle in vivo, we developed a microfluidic sperm-sorting chip with a viscous medium (polyvinylpyrrolidone: PVP) to imitate the biophysical environment mimic system of the human cervical canal. The material...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 34680555
DOI: 10.3390/biomedicines9101439

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