Article
Development of a KRAS-Associated Metabolic Risk Model for Prognostic Prediction in Pancreatic Cancer.
BioMed research international - 1 Jan 2021
Ma Zuyi, Li Zhenchong, Ma Zuguang, Zhou Zixuan, Zhuang Hongkai, Liu Chunsheng, Huang Bowen, Zou Yiping, Zheng Zehao, Yang LinLing, Gong Yuanfeng, Huang Shanzhou, Zhou Qi, Zhang Chuanzhao, Hou Baohua
Abstract excerpt
BACKGROUND: KRAS was reported to affect some metabolic genes and promote metabolic reprogramming in solid tumors. However, there was no comprehensive analysis to explore KRAS-associated metabolic signature or risk model for pancreatic cancer (PC). METHODS: In the current study, multiple bioinformatics analyses were used to identify differentially expressed metabolic genes based on KRAS mutation status in PC....
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