Article
Hemiplegic Migraine Associated With PRRT2 Variations: A Clinical and Genetic Study.
Neurology - 4 Jan 2022
Riant Florence, Roos Caroline, Roubertie Agathe, Barbance Cécile, Hadjadj Jessica, Auvin Stéphane, Baille Guillaume, Beltramone Marion, Boulanger Cécile, Cahn Alice, Cata Florina, Cheuret Emmanuel, Cuvellier Jean-Christophe, Defo Antoine, Demarquay Genevieve, Donnet Anne, Gaillard Nicolas, Massardier Evelyne, Guy Nathalie, Lamoureux Sylvie, Le Moigno Laurence, Lucas Christian, Ratiu Diana, Redon Sylvain, Rey Caroline, Thauvin Christel, Viallet François, Tournier-Lasserve Elisabeth, Ducros Anne
Abstract excerpt
BACKGROUND AND OBJECTIVE: PRRT2 variants have been reported in a few cases of patients with hemiplegic migraine. To clarify the role of PRRT2 in familial hemiplegic migraine, we studied this gene in a large cohort of affected probands. METHODS: PRRT2 was analyzed in 860 probands with hemiplegic migraine, and PRRT2 variations were identified in 30 probands. Genotyping of relatives identified a total of 49 persons...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.