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Article

Dynamics of Polarized Macrophages and Activated CD8+ Cells in Heart Tissue of Atlantic Salmon Infected With Piscine Orthoreovirus-1.

Frontiers in immunology - 1 Jan 2021

Malik Muhammad Salman, Nyman Ingvild Berg, Wessel Øystein, Dahle Maria K, Rimstad Espen

Abstract excerpt

Piscine orthoreovirus (PRV-1) infection causes heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar). The virus is also associated with focal melanized changes in white skeletal muscle where PRV-1 infection of macrophages appears to be important. In this study, we studied the macrophage polarization into M1 (pro-inflammatory) and M2 (anti-inflammatory) phenotypes during...

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Identifiers

PMID: 34603301
DOI: 10.3389/fimmu.2021.729017
PMCID: PMC8481380

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Dynamics of Polarized Macrophages and Activated CD8+ Cells in Heart Tissue of Atlantic Salmon Infected With Piscine Orthoreovirus-1.PMID 34603301Read ↗

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