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Article

Alteration of the Early Development Environment by Maternal Diet and the Occurrence of Autistic-like Phenotypes in Rat Offspring.

International journal of molecular sciences - 7 Sept 2021

Gawlińska Kinga, Gawliński Dawid, Kowal-Wiśniewska Ewelina, Jarmuż-Szymczak Małgorzata, Filip Małgorzata

Abstract excerpt

Epidemiological and preclinical studies suggest that maternal obesity increases the risk of autism spectrum disorder (ASD) in offspring. Here, we assessed the effects of exposure to modified maternal diets limited to pregnancy and lactation on brain development and behavior in rat offspring of both sexes. Among the studied diets, a maternal high-fat diet (HFD) disturbed the expression of ASD-related genes...

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Source

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Identifiers

PMID: 34575826
DOI: 10.3390/ijms22189662
PMCID: PMC8472469

Genes

TAOK2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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